[Renal urinary shear stress: a novel actor in nephropathies].

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Gonzalez, Julien | Essig, Marie | Klein, Julie | Caubet, Cécile | Dissard, Romain | Bascands, Jean-Loup | Schanstra, Joost P | Buffin-Meyer, Bénédicte

Edité par CCSD ; EDP Sciences -

International audience. The role of fluid shear stress is well established in vascular pathophysiology. However, urinary shear stress now also appears as a key mechanism in the regulation of renal function. In addition, there is a growing body of evidence showing that modified urinary shear stress is involved in the development of nephropathies. Therefore we review here the state-of-the-art on the pathophysiological roles of urinary shear stress.

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