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Expansion of Highly Differentiated Cytotoxic Terminally Differentiated Effector Memory CD8+ T Cells in a Subset of Clinically Stable Kidney Transplant Recipients: A Potential Marker for Late Graft Dysfunction

Archive ouverte | Yap, Michelle | CCSD

S.B. and N.D. contributed equally to this work.. International audience. Despite the effectiveness of immunosuppressive drugs, kidney transplant recipients still face late graft dysfunction. Thus, it is necessary to...

Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients

Archive ouverte | Dumontet, Erwan | CCSD

International audience. BACKGROUND AND AIMS: The beneficial effect of one graft on another has been reported in combined transplantation but the associated mechanisms and biological influence of each graft have not ...

The Blood of Healthy Individuals Exhibits CD8 T Cells with a Highly Altered TCR Vb Repertoire but with an Unmodified Phenotype

Archive ouverte | Degauque, Nicolas | CCSD

International audience. CD8 T cell clonal expansions (TCE) have been observed in elderly, healthy individuals as well in old mice, and have been associated with the ageing process. Both chronic latent and non-persis...

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