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Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity.

Archive ouverte | Mahuzier, Alexia | CCSD

International audience. Cilia are at the core of planar polarity cellular events in many systems. However, the molecular mechanisms by which they influence the polarization process are unclear. Here, we identify the...

Dishevelled stablisation at the cilium by RPGRIP1L is essential for planar cell polarity

Archive ouverte | Schneider-Maunoury, Sylvie | CCSD

International audience

Loss of the Reissner Fiber and increased URP neuropeptide signaling underlie scoliosis in a zebrafish ciliopathy mutant

Archive ouverte | Vesque, Christine | CCSD

SUMMARY Cilia-driven movements of the cerebrospinal fluid (CSF) are involved in zebrafish axis straightness, both in embryos and juveniles [1, 2]. In embryos, axis straightness requires cilia-dependent assembly of the Reissner fib...

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