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Cytokine and gene transcription profiles of immune responses elicited by HIV lipopeptide vaccine in HIV-negative volunteers.

Archive ouverte | Richert, Laura | CCSD

International audience. OBJECTIVE: To dissect the biological mechanisms involved in the cellular responses to a candidate vaccine containing 5 HIV peptides coupled to a palmytoil tail (HIV-LIPO-5) in healthy volunte...

A novel approach for biomarker selection and the integration of repeated measures experiments from two assays.

Archive ouverte | Liquet, Benoit | CCSD

International audience. BACKGROUND: High throughput 'omics' experiments are usually designed to compare changes observed between different conditions (or interventions) and to identify biomarkers capable of characte...

Optimization and evaluation of Luminex performance with supernatants of antigen-stimulated peripheral blood mononuclear cells

Archive ouverte | Surénaud, Mathieu | CCSD

International audience. AbstractBackgroundThe Luminex bead-based multiplex assay is useful for quantifying immune mediators such as cytokines and chemokines. Cross-comparisons of reagents for this technique from dif...

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