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Ultrasmall rigid particles as multimodal probes for medical applications.

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Lux, François | Mignot, Anna | Mowat, Pierre | Louis, Cédric | Dufort, Sandrine | Bernhard, Claire | Denat, Franck | Boschetti, Frédéric | Brunet, Claire | Antoine, Rodolphe | Dugourd, Philippe | Laurent, Sophie | Elst, Luce Vander | Muller, Robert | Sancey, Lucie | Josserand, Véronique | Coll, Jean-Luc | Stupar, Vasile | Barbier, Emmanuel | Rémy, Chantal | Broisat, Alexis | Ghezzi, Catherine | Le Duc, Géraldine | Roux, Stéphane | Perriat, Pascal | Tillement, Olivier

Edité par CCSD ; Wiley-VCH Verlag -

International audience. Ultrasmall but multifunctional: Rigid imaging particles that are smaller than 5 nm in size can be obtained in a top-down process starting from a core–shell structure (core=gadolinium oxide; shell=polysiloxane). They represent the first multifunctional silica-based particles that are sufficiently small to escape hepatic clearance and enable animal imaging by four complementary techniques

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