Sleep contributes to the strengthening of some memories over others, depending on hippocampal activity at learning.. Sleep contributes to the strengthening of some memories over others, depending on hippocampal activity at learning.: Sleep, the hippocampus and memory consolidation

Archive ouverte

Rauchs, Géraldine | Feyers, Dorothée | Landeau, Brigitte | Bastin, Christine | Luxen, André | Maquet, Pierre | Collette, Fabienne

Edité par CCSD ; Society for Neuroscience -

International audience. Memory consolidation benefits from sleep. In addition to strengthening some memory traces, another crucial, albeit overlooked, function of memory is to erase irrelevant information. Directed forgetting is an experimental approach consisting in presenting "to be remembered" and "to be forgotten" information that allows selectively decreasing or increasing the strength of individual memory traces according to the instruction provided at learning. This paradigm was used in combination with functional MRI to determine, in humans, what specifically triggers at encoding sleep-dependent compared with time-dependent consolidation. Our data indicate that relevant items that subjects strived to memorize are consolidated during sleep to a greater extent than items that participants did not intend to learn. This process appears to depend on a differential activation of the hippocampus at encoding, which acts as a signal for the offline reprocessing of relevant memories during postlearning sleep episodes.

Suggestions

Du même auteur

Neural correlates of successful memory retrieval in aging: Do executive functioning and task difficulty matter?

Archive ouverte | Angel, Lucie | CCSD

International audience. The current experiment aimed to explore age differences in brain activity associated with successful memory retrieval in older adults with different levels of executive functioning, at differ...

Association of Sleep-Disordered Breathing With Alzheimer Disease Biomarkers in Community-Dwelling Older Adults: A Secondary Analysis of a Randomized Clinical Trial

Archive ouverte | André, Claire | CCSD

International audience. IMPORTANCE:Increasing evidence suggests that sleep-disordered breathing (SDB) increases the risk of developing Alzheimer clinical syndrome. However, the brain mechanisms underlying the link b...

Meditation dosage predicts self- and teacher-perceived responsiveness to an 18-month randomised controlled trial

Archive ouverte | Schlosser, Marco | CCSD

International audience

Chargement des enrichissements...