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Evaluation of an hPXR reporter gene assay for the detection of aquatic emerging pollutants: screening of chemicals and application to water samples.

Archive ouverte | Creusot, Nicolas | CCSD

International audience. Many environmental endocrine-disrupting compounds act as ligands for nuclear receptors. Among these receptors, the human pregnane X receptor (hPXR) is well described as a xenobiotic sensor to...

Distribution of steroid- and dioxin-like activities between sediments, POCIS and SPMD in a French river subject to mixed pressures

Archive ouverte | Creusot, Nicolas | CCSD

International audience. The contamination of aquatic systems by endocrine disrupting chemicals (EDCs) is now a widely established fact. Nevertheless, there is still a scarcity of knowledge concerning the source, tra...

Combined use of passive sampling and in vitro bioassays for the detection of emerging pollutants in surface water

Archive ouverte | Creusot, Nicolas | CCSD

River systems are contaminated by various chemicals, a number of which are described as endocrine disrupting compounds (EDCs) that can be monitored by using in vitro receptor-based bioassays. While estrogen (ER) and aryl hydrocarb...

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