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Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

Archive ouverte | Sancho-Shimizu, Vanessa | CCSD

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Archive ouverte | Guo, Yiqi | CCSD

International audience. Autosomal dominant TLR3 deficiency has been identified as a genetic etiology of childhood herpes simplex virus 1 (HSV-1) encephalitis (HSE). This defect is partial, as it results in impaired,...

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Archive ouverte | Zhang, Shen-Ying | CCSD

International audience. Some Toll and Toll-like receptors (TLRs) provide immunity to experimental infections in animal models, but their contribution to host defense in natural ecosystems is unknown. We report a dom...

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