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Transient increase in recurrent inhibition in amyotrophic lateral sclerosis as a putative protection from neurodegeneration

Archive ouverte | Sangari, Sina | CCSD

International audience. Aim: Adaptive mechanisms in spinal circuits are likely involved in homeostatic responses to maintain motor output in amyotrophic lateral sclerosis. Given the role of Renshaw cells in regulati...

Synaptic dynamics linked to widespread elevation of h-reflex before peripheral denervation in amyotrophic lateral sclerosis

Archive ouverte | Sangari, Sina | CCSD

International audience. Changes in Hoffmann reflex (H-reflex) exhibit heterogeneity among patients with amyotrophic lateral sclerosis (ALS), likely due to phenotype diversity. Current knowledge primarily focuses on ...

Multi-Parametric Spinal Cord MRI as Potential Progression Marker in Amyotrophic Lateral Sclerosis

Archive ouverte | El Mendili, Mohamed-Mounir | CCSD

International audience. Objective: To evaluate multimodal MRI of the spinal cord in predicting disease progression and one-year clinical status in amyotrophic lateral sclerosis (ALS) patients. Materials and Methods:...

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