Which Factors Determine Affected Sites in Hidradenitis Suppurativa?. Condition de réalisation de la cytaphérèse pour la mise à disposition du matériel biologique nécessaire à la production de CAR T-cells commerciaux : avis d’experts proposé par la SFGM-TC

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Benhadou, Farida | Villani, Axel Patrice | Guillem, Philippe

Edité par CCSD ; Karger -

International audience. Background: The factors that determine whether an area of the body will be affected by hidradenitis suppurativa (HS) are unknown. Methods: To address these factors, we performed multivariate regression analyses in a cohort of 1,138 patients. Results: We found that the body sites affected occurred in specific combinations that were influenced by sex and body mass index. We also revealed unexpected correlations between some sites and other comorbidities such as inflammatory diseases, acne conglobata, or dissecting folliculitis of the scalp. Conclusion: Such correlations are crucial to unravel a disease as variable as HS and identify pathophysiological mechanisms to enable the provision of personalized management.

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