Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial
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Oaknin, Ana | Gladieff, Laurence | Martínez-García, Jerónimo | Villacampa, Guillermo | Takekuma, Munetaka | de Giorgi, Ugo | Lindemann, Kristina | Woelber, Linn | Colombo, Nicoletta | Duska, Linda | Leary, Alexandra | Godoy-Ortiz, Ana | Nishio, Shin | Angelergues, Antoine | Rubio, Maria Jesús | Fariñas-Madrid, Lorena | Yamaguchi, Satoshi | Lorusso, Domenica | Ray-Coquard, Isabelle | Manso, Luis | Joly, Florence | Alarcón, Jesús | Follana, Philippe | Romero, Ignacio | Lebreton, Coriolan | Pérez-Fidalgo, J Alejandro | Yunokawa, Mayu | Dahlstrand, Hanna | d'Hondt, Véronique | Randall, Leslie | Abadie-Lacourtoisie, Sophie | Andreetta, Claudia | Anzizar, Nerea | Aoki, Daiseuke | Barretina-Ginesta, Maria-Pilar | Battista, Marco | Bellier, Charlotte | Bentzen, Anne Gry | Berton, Dominique | Billemont, Bertrand | Bjørge, Line | Bjurberg, Maria | Black, Destin | Bologna, Alessandra | Braicu, Elena Ioana | Casanova, Claudia | Chekerov, Radoslav | Chevalier, Annick | Cueva, Juan Fernando | Czogalla, Bastian | Delanoy, Nicolas | Denschlag, Dominik | Derke, Oscar | Eichbaum, Michael | Enomoto, Takayuki | Esteban, Carmen | Fabbro, Michel | Fehm, Tanja | Ferrero, Annamaria | Fleisch, Markus | Floquet, Anne | Frassoldati, Antonio | Gaba, Lydia | Gadducci, Angiolo | García, Yolanda | Geuna, Elena | Guerra, Eva | Hanker, Lars | Hardy-Bessard, Anne-Claire | Harter, Philipp | Hasegawa, Kosei | Hellman, Kristina | Herrero, Ana | Hilpert, Felix | Katsaros, Dionyssios | Koegel, Matthias | Koliadi, Anthoula | Kurtz, Jean-Emmanuel | Lampe, Bjoern | Lissoni, Andrea Alberto | Lortholary, Alain | Mangili, Giorgia | Mansi, Laura | Marmé, Frederik | Mathews, Cara | Mina, William | Minobe, Shinichiro | Moxley, Katherine | Nagao, Shoji | Nicoletto, Ornella | Nishino, Koji | Nishio, Hiroshi | Onstad, Michaela | Pardo, Beatriz | Pisano, Carmela | Poveda, Andrés | Radosa, Julia | Redondo, Andrés | Richardson, Debra | Ronzino, Graziana | Selle, Frederic | Takeshima, Nobuhiro | Tasca, Giulia | Tewari, Krishnansu | Todo, Yukiharu | Valabrega, Giorgio | Wimberger, Pauline | You, Benoît
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International audience.
The GOG240 trial established bevacizumab with chemotherapy as standard first-line therapy for metastatic or recurrent cervical cancer. In the BEATcc trial (ENGOT-Cx10-GEICO 68-C-JGOG1084-GOG-3030), we aimed to evaluate the addition of an immune checkpoint inhibitor to this standard backbone.
