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Peripheral Blood Mononuclear Cells (PBMCs) to Dissect the Underlying Mechanisms of Bone Disease in Chronic Kidney Disease and Rare Renal Diseases

Archive ouverte | Bernardor, Julie | CCSD

International audience. Purpose of review: To describe the methods that can be used to obtain functional and mature osteoclasts from peripheral blood mononuclear cells (PBMCs) and report the data obtained with this ...

Response to Cysteamine in Osteoclasts Obtained from Patients with Nephropathic Cystinosis: A Genotype/Phenotype Correlation

Archive ouverte | Quinaux, Thomas | CCSD

International audience. Bone complications of cystinosis have been recently described. The main objectives of this paper were to determine in vitro the impact of CTNS mutations and cysteamine therapy on human osteoc...

X-Linked Hypophosphatemia, Not Only a Skeletal Disease But Also a Chronic Inflammatory State

Archive ouverte | Méaux, Marie-Noëlle | CCSD

International audience. Abstract Context X-linked hypophosphatemia (XLH) is a rare genetic disease caused by a primary excess of fibroblast growth factor 23 (FGF23). FGF23 has been associated with inflammation and i...

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