Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis

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Eijkemans, Marianne | Mommers, Monique | Harskamp-van Ginkel, Margreet | Vrijkotte, Tanja | Ludvigsson, Johnny | Faresjö, Åshild | Bergstrom, Anna | Ekström, Sandra | Grote, Veit | Koletzko, Berthold | Bønnelykke, Klaus | Eliasen, Anders Ulrik | Bager, Peter | Melbye, Mads | Annesi-Maesano, Isabella | Baiz, Nour | Barros, Henrique | Santos, Ana Cristina | Duijts, Liesbeth | Mensink-Bout, Sara | Flexeder, Claudia | Koletzko, Sibylle | Schikowski, Tamara | Eggesbø, Merete Åse | Lenters, Virissa | Fernández-Tardón, Guillermo | Subiza-Perez, Mikel | Garcia-Aymerich, Judith | López-Vicente, Mónica | Sunyer, Jordi | Torrent, Maties | Ballester, Ferran | Kelleher, Cecily | Mehegan, John | Berg, Andrea Von | Herberth, Gunda | Standl, Marie | Kuehni, Claudia | Pedersen, Eva | Jansen, Maria | Gehring, Ulrike | Boer, Jolanda | Devereux, Graham | Turner, Steve | Peltola, Ville | Lagström, Hanna | Inskip, Hazel | Pike, Katharine | Dalmeijer, Geertje | van Der Ent, Cornelis | Thijs, Carel

Edité par CCSD ; BMJ Journals -

International audience. Objectives: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study. Design: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined. Setting: Children aged 0-18 years from 26 European birth cohorts. Participants: 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood. Main outcome measure: Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV 1 ), FEV 1 /forced vital capacity) at age 6-18 years. Results: Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results. Conclusions: Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.

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