Suggestions

Du même auteur

Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma

Archive ouverte | Lin, Shu-Hong | CCSD

International audience. Background: Ewing sarcoma (EwS) is a rare, aggressive solid tumor of childhood, adolescence and young adulthood associated with pathognomonic EWSR1-ETS fusion oncoproteins altering transcript...

Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility

Archive ouverte | Machiela, Mitchell, J | CCSD

International audience. Ewing sarcoma (EWS) is a pediatric cancer characterized by the EWSR1-FLI1 fusion. We performed a genome-wide association study of 733 EWS cases and 1346 unaffected individuals of European anc...

STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma

Archive ouverte | Surdez, Didier | CCSD

International audience. STAG2, a cohesin family gene, is among the most recurrently mutated genes in cancer. STAG2 loss of function (LOF) is associated with aggressive behavior in Ewing sarcoma, a childhood cancer d...

Chargement des enrichissements...