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Sphingomyelins in mosquito saliva modify the host lipidome to enhance transmission of flaviviruses by promoting viral protein levels

Archive ouverte | Medkour, Hacene | CCSD

Mosquito saliva plays a determining role in flavivirus transmission. Here, we discover and elucidate how salivary lipids enhance transmission. Building upon our discovery of salivary extracellular vesicles (EV), we determined that...

Zika virus infection modulates the metabolomic profile of microglial cells

Archive ouverte | Diop, Fode | CCSD

International audience. Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family. Although infection with ZIKV generally leads to mild disease, its recent emergence in the Americas has been associated w...

Lipid Interactions Between Flaviviruses and Mosquito Vectors

Archive ouverte | Vial, Thomas | CCSD

International audience. Mosquito-borne flaviviruses, such as dengue (DENV), Zika (ZIKV), yellow fever (YFV), West Nile (WNV), and Japanese encephalitis (JEV) viruses, threaten a large part of the human populations. ...

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