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Involvement of the dependence receptor TRKC and its ligand NT-3 in tumorigenesis : from basic research to targeted therapy. Implication du récepteur à dépendance TRKC et de son ligand NT-3 en cancérogénèse : de la recherche fondamentale à la thérapeutique

Archive ouverte | Genevois, Anne-Laure | CCSD

The neurotrophin receptor TrkC was recently identified as a dependence receptor, and, as such, it triggers apoptosis in the absence of its ligand, NT-3. Indeed cells that express these receptors are thought to be dependent on liga...

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Archive ouverte | Kubicek, Pierre | CCSD

International audience. Abstract Background The initial management of patients with sarcoma is a critical issue. We used the nationwide French National Cancer Institute -funded prospective sarcoma database NETSARC t...

Locally aggressive rarely metastazing tumors and low-grade sarcoma in children, adolescents and young adults: The benefits of a national network

Archive ouverte | Brisset, Claire | CCSD

International audience

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