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Mechanistic insights into the role of septins in mammalian cell morphogenesis

Archive ouverte | Martins, Carla, Silva | CCSD

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Archive ouverte | Castro-Linares, Gerard | CCSD

International audience. Septins are a family of conserved eukaryotic GTP-binding proteins that can form cytoskeletal filaments and higher-order structures from hetero-oligomeric complexes. They interact with other c...

Human septins organize as octamer-based filaments and mediate actin-membrane anchoring in cells

Archive ouverte | Martins, Carla Silva | CCSD

International audience. Septins are cytoskeletal proteins conserved from algae and protists to mammals. A unique feature of septins is their presence as heteromeric complexes that polymerize into filaments in soluti...

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