Afficher la couverture 'Pharmacomodulation of a ligand targeting the HBV capsid hydrophobic pocket | Briday, Mathilde' en grand format
/5

0 avis

Pharmacomodulation of a ligand targeting the HBV capsid hydrophobic pocket

Archive ouverte

Briday, Mathilde | Hallé, François | Lecoq, Lauriane | Radix, Sylvie | Martin, Juliette | Montserret, Roland | Dujardin, Marie | Fogeron, Marie-Laure | Nassal, Michael | Meier, Beat, H | Lomberget, Thierry | Böckmann, Anja

Edité par CCSD ; The Royal Society of Chemistry -

International audience. Small-molecule binding to the Hepatitis B virus core protein hydrophobic pocket, a possible strategy for targeting viral particle assembly.

Suggestions

Du même auteur

Pharmacomodulation of a ligand targeting the HBV capsid hydrophobic pocket

Archive ouverte | Briday, Mathilde | CCSD

International audience. Hepatitis B virus (HBV) is a small enveloped retrotranscribing DNA virus and an important human pathogen. Its capsid-forming core protein (Cp) features a hydrophobic pocket proposed to be cen...

Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR. Élucidation moléculaire des assemblages anormaux de la protéine de capside du virus de l'hépatite B induits par les médicaments, par RMN à l'état solide.

Archive ouverte | Lecoq, Lauriane | CCSD

International audience. Hepatitis B virus (HBV) capsid assembly modulators (CAMs) represent a recent class of anti-HBV antivirals. CAMs disturb proper nucleocapsid assembly, by inducing formation of either aberrant ...

A pocket-factor-triggered conformational switch in the hepatitis B virus capsid

Archive ouverte | Lecoq, Lauriane | CCSD

International audience. Viral hepatitis is growing into an epidemic illness, and it is urgent to neutralize the main culprit, hepatitis B virus (HBV), a small-enveloped retrotranscribing DNA virus. An intriguing obs...

Chargement des enrichissements...