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Amyloid, tau, and astrocyte pathology in autosomal-dominant Alzheimer’s disease variants: AβPParc and PSEN1DE9

Archive ouverte | Lemoine, Laetitia | CCSD

International audience. Autosomal-dominant Alzheimer’s disease (ADAD) may be associated with atypical amyloid beta deposits in the brain. In vivo amyloid imaging using 11 C-Pittsburgh compound B (PiB) tracer has sho...

Clinical Effect of Early vs Late Amyloid Positron Emission Tomography in Memory Clinic Patients

Archive ouverte | Altomare, Daniele | CCSD

International audience. Importance Amyloid positron emission tomography (PET) allows the direct assessment of amyloid deposition, one of the main hallmarks of Alzheimer disease. However, this technique is currently ...

Longitudinal tau and metabolic PET imaging in relation to novel CSF tau measures in Alzheimer’s disease

Archive ouverte | Leuzy, Antoine | CCSD

International audience. Purpose: Studies comparing CSF and PET tau biomarkers have included only commercial CSF assays examining specific phosphorylation sites (e.g. threonine 181, P-tau181p) and mid-domain tau (i.e...

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