Impact of dielectrophoresis (DEP) on fiber-based piezoelectric composites is investigated. The combination of fiber filler with DEP results in the greatest piezoelectric coefficient to volume content ratio yet developed. The structured piezoelectric composite is employed as biosensor for self-monitoring vascular grafts able to detect clot development. The biosensor connected to an inductive coil and implemented into a vascular simulator proofs its ability to detect clots.