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Prospective Whole-Genome Sequencing in Tuberculosis Outbreak Investigation, France, 2017–2018

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Genestet, Charlotte | Tatai, Caroline | Berland, Jean-Luc | Claude, Jean-Baptiste | Westeel, Emilie | Hodille, Elisabeth | Fredenucci, Isabelle | Rasigade, Jean-Philippe | Ponsoda, Michael | Jacomo, Véronique | Vachée, Anne | Gaudart, Alice | Gaillard, Jean-Louis | Roux, Anne-Laure | Ader, Florence | Tararbit, Karim | Terpant, Garance | Bryant, Juliet | Lina, Gérard | Dumitrescu, Oana

Edité par CCSD ; Centers for Disease Control and Prevention -

International audience. During June 2017–April 2018, active tuberculosis with Beijing SIT1 isolates was diagnosed in 14 persons living in 4 distant cities in France. Whole-genome sequencing indicated that these patients belonged to a single transmission chain. Whole-genome sequencing–based laboratory investigations enabled prompt tracing of linked cases to improve tuberculosis control.

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