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How the Human T-lymphotropic Virus type 1protects its RNAs by hijacking key cellular factors

Archive ouverte | Jalinot, Pierre | CCSD

International audience

The SARS-CoV-2 nucleocapsid protein interferes with the full enzymatic activation of UPF1 and its interaction with UPF2. La protéine nucléocapside du SARS-CoV-2 interfère avec l'activation enzymatique complète de UPF1 et son interaction avec UPF2.

Archive ouverte | Nuccetelli, Veronica | CCSD

International audience. The nonsense-mediated mRNA decay (NMD) pathway triggers the degradation of defective mRNAs and governs the expression of mRNAs with specific characteristics. Current understanding indicates t...

The SARS-CoV-2 nucleocapsid protein inhibits the cellular Nonsense-Mediated mRNA Decay (NMD) pathway preventing the full enzymatic activation of UPF1

Archive ouverte | Nuccetelli, Veronica | CCSD

The Nonsense-mediated mRNA decay (NMD) pathway triggers the degradation of defective mRNAs and governs the expression of mRNAs with specific characteristics. Current understanding indicates that NMD is often significantly suppress...

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