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Unlocking Single-Cell Immunometabolism Research: A Call for Accessible Tools

Archive ouverte | Cosgrove, Jason | CCSD

International audience. Recent technological advances permit the profiling of metabolic changes in single cells, which sheds light on how metabolism regulates immune responses. We advocate for accessible and standar...

Metabolically Primed Multipotent Hematopoietic Progenitors Fuel Innate Immunity

Archive ouverte | Cosgrove, Jason | CCSD

Following infection, hematopoietic stem and progenitor cells (HSPCs) support immunity by increasing the rate of innate immune cell production but the metabolic cues that guide this process are unknown. To address this question, we...

Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells

Archive ouverte | Sommerkamp, Pia | CCSD

International audience. Abstract Hematopoietic stem cells (HSCs) and distinct multipotent progenitor (MPP) populations (MPP1-4) contained within the Lin−Sca-1+c-Kit+ (LSK) compartment have previously been identified...

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