Pharmaceutical cancer care for haematology patients on oral anticancer drugs: Findings from an economic, clinical and organisational analysis

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Zerbit, Jeremie | Kroemer, Marie | Fuchs, Basile | Detroit, Marion | Decroocq, Justine | Vignon, Marguerite | Willems, Lise | Deau-Fischer, Bénédicte | Franchi, Patricia | Deschamps, Paul | Contejean, Adrien | Grignano, Eric | Fouquet, Guillemette | Birsen, Rudy | Mondesir, Johanna | Rocquet, Mathieu | Huon, Jean-François | Batista, Rui | Marty-Reboul, Jeanne | Bouscary, Didier

Edité par CCSD ; Wiley -

International audience. Objective: The clinical benefit of pharmaceutical cares in improving the quality-of-care outcomes is well demonstrated. Clinical pharmacy services are not systematically deployed in cancer units in the absence of economic data. The aim of this prospective, observational 1-year study was to evaluate the clinical, economic and organisational impacts of pharmaceutical care into a multidisciplinary day hospital for patients treated with oral cancer drugs.Methods: All pharmacists' interventions (PI) were documented and their impact and the probability of adverse drug events were assessed using the clinical, economic and organisational tool.Results: Among 360 admissions, an average of 1.81 PI per admission was accepted. Among 452 PI leading to a clinical benefit on the patient, 16.9% had a major impact, and 1.9% had an impact on survival. The large majority of PIs (87%) increased the quality-of-care organisation. The budget impact model showed a total cost savings and cost avoidance of €539,047 per year and a cost-benefit ratio of 7.07:1. The direct cost-benefit was €201,741, and the cost avoidance was €337,306.Conclusion: Multidisciplinary care and pharmaceutical care are key elements to improve cancer patients' outcomes and avoid evitable healthcare costs.

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