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Characteristics and outcomes of gemcitabine-associated pulmonary hypertension

Archive ouverte | Mouillot, Pierre | CCSD

International audience. Background Despite its known cardiac and lung toxicities, the chemotherapy drug gemcitabine has only rarely been associated with pulmonary hypertension (PH), and the underlying mechanism rema...

Pulmonary hypertension associated with diazoxide: the SUR1 paradox

Archive ouverte | Montani, David | CCSD

International audience. The ATP-sensitive potassium channels and their regulatory subunits, sulfonylurea receptor 1 (SUR1/Kir6.2) and SUR2/Kir6.1, contribute to the pathophysiology of pulmonary hypertension (PH). Lo...

Association Between Initial Treatment Strategy and Long-term Survival in Pulmonary Arterial Hypertension

Archive ouverte | Boucly, Athénaïs | CCSD

International audience. Rationale: The relationship between the initial treatment strategy and survival in pulmonary arterial hypertension (PAH) remains uncertain. Objectives: To evaluate the long-term survival of p...

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