Measurement of hypocretin/orexin content in the mouse brain using an enzyme immunoassay: the effect of circadian time, age and genetic background

Archive ouverte | Lin, L. | CCSD

International audience. The hypocretins (1 and 2) have emerged as key regulators of sleep and wakefulness. We developed a high-throughput enzyme immunoassay (EIA) to measure total brain hypocretin levels from large ...

Role and origin of the GABAergic innervation of dorsal raphe serotonergic neurons.

Archive ouverte | Gervasoni, D. | CCSD

Extracellular electrophysiological recordings in freely moving cats have shown that serotonergic neurons from the dorsal raphe nucleus (DRN) fire tonically during wakefulness, decrease their activity during slow wave sleep (SWS), ...

Posterior hypothalamus and regulation of vigilance states.

Archive ouverte | Goutagny, Romain | CCSD