Suggestions

Du même auteur

Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease

Archive ouverte | Noelker, Carmen | CCSD

International audience. In mammalians, toll-like receptors (TLR) signal-transduction pathways induce the expression of a variety of immune-response genes, including inflammatory cytokines. It is therefore plausible ...

Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease

Archive ouverte | Noelker, Carmen | CCSD

International audience. BackgroundIncreasing evidence suggests that inflammation associated with microglial cell activation in the substantia nigra (SN) of patients with Parkinson disease (PD) is not only a conseque...

Glucocerebrosidase deficiency and mitochondrial impairment in experimental Parkinson disease

Archive ouverte | Noelker, Carmen | CCSD

International audience. Gaucher disease is an autosomal recessive disease, caused by a lack or functional deficiency of the lysosomal enzyme, glucocerebrosidase (GCase). Recently, mutations in the glucocerebrosidase...

Chargement des enrichissements...