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Cartilage tissue engineering: Molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction

Archive ouverte | Demoor, Magali | CCSD

International audience. Background: Articular cartilage defects are a veritable therapeutic problem because therapeutic options are very scarce. Due to the poor self-regeneration capacity of cartilage, minor cartila...

Characterization and use of equine bone marrow mesenchymal stem cells in horse cartilage engineering

Archive ouverte | Branly, Thomas | CCSD

National audience. PURPOSE: Articular cartilage is of great importance for physiological mobility. The structure and the function of this tissue which is characterized by a poor self-repair capacity are frequently d...

Enhanced chondrogenesis of bone marrow-derived stem cells by using a combinatory cell therapy strategy with BMP-2/TGF-β1, hypoxia, and COL1A1/HtrA1 siRNAs

Archive ouverte | Legendre, Florence | CCSD

International audience. Mesenchymal stem cells (MSCs) hold promise for cartilage engineering. Here, we aimed to determine the best culture conditions to induce chondrogenesis of MSCs isolated from bone marrow (BM) o...

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