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Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite

Archive ouverte | Kotila, Tommi | CCSD

International audience. Abstract Actin polymerization generates forces for cellular processes throughout the eukaryotic kingdom, but our understanding of the ‘ancient’ actin turnover machineries is limited. We show ...

Tropomyosin isoforms specify functionally distinct actin filament populations in vitro

Archive ouverte | Gateva, Gergana | CCSD

Actin filaments assemble into a variety of networks to provide force for diverse cellular processes [1]. Tropomyosins are coiled-coil dimers that form head-to-tail polymers along actin filaments and regulate interactions of other ...

A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics

Archive ouverte | Colombo, Jessica | CCSD

International audience. Actin polymerization provides force for vital processes of the eukaryotic cell, but our understanding of actin dynamics and energetics remains limited due to the lack of highquality probes. M...

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