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Telomeric C‐circles localize at nuclear pore complexes in Saccharomyces cerevisiae. Sciences de la vie

Archive ouverte | Aguilera, Paula | CCSD

International audience. As in human cells, yeast telomeres can be maintained in cells lacking telomerase activity by recombination-based mechanisms known as ALT (Alternative Lengthening of Telomeres). A hallmark of ...

Telomeric circles localize to the Nuclear Pore Complex and participate to telomere recombination in the absence of telomerase

Archive ouverte | Simon, Marie-Noëlle | CCSD

International audience

The nuclear pore complex prevents sister chromatid recombination during replicative senescence

Archive ouverte | Aguilera, Paula | CCSD

International audience. The Nuclear Pore Complex (NPC) has emerged as an important hub for processing various types of DNA damage. Here, we uncover that fusing a DNA binding domain to the NPC basket protein Nup1 red...

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