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Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists.

Archive ouverte | Germain, Pierre | CCSD

International audience. Retinoic acid receptors (RARs) are ligand-dependent transcription factors that control a plethora of physiological processes. RARs exert their functions by regulating gene networks controllin...

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Archive ouverte | Pogenberg, Vivian | CCSD

International audience. Retinoid receptors (RARs and RXRs) are ligand-activated transcription factors that regulate the transcription of target genes by recruiting coregulator complexes at cognate promoters. To unde...

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Archive ouverte | Sanglier, Sarah | CCSD

International audience. Retinoid receptors are ligand‐dependent transcription factors belonging to the nuclear receptor superfamily. Retinoic acid (RARα, β, γ) and retinoid X (RXRα, β, γ) receptors mediate the retin...

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