Syracuse

Geriatric assessment and quality of life for 2 years in older patients with head and neck cancer

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Lafont, Charlotte | Paillaud, Elena | Caillet, Philippe | Laurent, Marie | Canouï-Poitrine, Florence | Bertolus, Chloe | Baron, Melany | Bouvard, Eric | Salvan, Didier | Chaumette, Laurence | de Decker, Laure | Piot, Benoit | Barry, Beatrix | Raynaud-Simon, Agathe | Sauvaget, Elisabeth | Minard, Aurelien | Anota, Amelie | Panjo, Henri | Brugel, Lydia

Edité par CCSD ; Oxford University Press (OUP) -

International audience. # The Author(s) 2024.Due to the location and toxicity of treatments, head and neck cancer (HNC) has a major impact on quality of life (QoL). Objective: to assess the effects of geriatric-assessment (GA)-driven interventions on QoL over 2 years in older adults with HNC. EGeSOR was a randomized study of HNC patients aged ≥65, receiving a pretreatment GA, a geriatric intervention and follow-up (intervention) or standard of care (control). The primary endpoint was QoL score using the European Organisation for Research and Treatment of Canceru2019s (EORTC QLQ-C30) and HNC (QLQ-HN35) QoL questionnaires over 24 months. In total, 475 patients were included (median age: 75.3; women: 31%; oral cancer: 44%). QoL scores improved over 24 months with various trajectories, without significant differences between the groups. A total of 74% of patients (interventional group) did not receive the complete intervention. Cancer characteristics, functional status, and risk of frailty were associated with change in the Global Health Status QoL score. There is a need to develop an alternative model of implementation such as patient-centered health-care pathways.

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