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Observing G4 formation and its resolution by Pif1 in real time by manipulation under magnetic tweezers

Archive ouverte | Valle-Orero, Jessica | CCSD

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Strand switching mechanism of Pif1 helicase induced by its collision with a G-quadruplex embedded in dsDNA

Archive ouverte | Valle-Orero, Jessica | CCSD

International audience. G-rich sequences found at multiple sites throughout all genomes may form secondary structures called G-quadruplexes (G4), which act as roadblocks for molecular motors. Among the enzymes thoug...

Folding and persistence times of intramolecular G-quadruplexes transiently embedded in a DNA duplex

Archive ouverte | Tran, Phong Lan Thao | CCSD

International audience. G-quadruplex (G4) DNA structures have emerged as important regulatory elements during DNA metabolic transactions. While many in vitro studies have focused on the kinetics of G4 formation with...

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