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Fungal cell wall components modulate our immune system

Archive ouverte | Briard, Benoit | CCSD

International audience. Invasive fungal infections remain highly problematic for human health. Collectively, they account for more than 1 million deaths a year in addition to more than 100 million mucosal infections...

Galactosaminogalactan activates the inflammasome to provide host protection

Archive ouverte | Briard, Benoit | CCSD

International audience. Galactosaminogalactan of Aspergillus fumigatus acts as a pathogen-associated molecular pattern that activates the NLRP3 inflammasome, which is crucial for anti-fungal host defence.Inflammasom...

Galactosaminogalactan of Aspergillus fumigatus, a bioactive fungal polymer.

Archive ouverte | Briard, Benoit | CCSD

International audience. Galactosaminogalactan (GAG) is an extracellular polysaccharide produced by the mycelium of the opportunistic human fungal pathogen Aspergillus fumigatus GAG is the first polysaccharide descri...

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