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Lsd1 prevents age-programed loss of beige adipocytes

Archive ouverte | Duteil, Delphine | CCSD

International audience. Significance Over time, beige adipocytes gain a white adipocyte morphology and lose their thermogenic activity. Here we show that levels of the epigenetic eraser lysine-specific demethylase 1...

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue

Archive ouverte | Duteil, Delphine | CCSD

Previous work indicated that lysine-specific demethylase 1 (Lsd1) can positively regulate the oxidative and thermogenic capacities of white and beige adipocytes. Here we investigate the role of Lsd1 in brown adipose tissue (BAT) a...

Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells

Archive ouverte | Tosic, Milica | CCSD

International audience. Abstract Satellite cells are muscle stem cells required for muscle regeneration upon damage. Of note, satellite cells are bipotent and have the capacity to differentiate not only into skeleta...

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