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Archive ouverte | Bleyzac, Nathalie | CCSD

International audience. The COVID-19 infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major public health issue worldwide, as no vaccines or drugs for prevention and treatment have ...

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Archive ouverte | Fermier, Nicolas | CCSD

International audience. The magnitude of drug-drug interactions mediated by cytochrome P450 (CYP) may depend on the genotype of polymorphic cytochromes. The objective of this study was to identify drug-drug interact...

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Archive ouverte | Tuloup, Vianney | CCSD

International audience. Rifamycins are widely used for treating mycobacterial and staphylococcal infections. Drug-drug interactions (DDI) caused by rifampicin (RIF) are a major issue. We used a model-based approach ...

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