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Stable accumulation of p67phox at the phagosomal membrane and ROS production within the phagosome

Archive ouverte | Tlili, Asma | CCSD

International audience. ABSTRACT Production of ROS by the leukocyte NADPH oxidase is essential for the destruction of pathogenic bacteria inside phagosomes. The enzyme is a complex of cytosolic and membranous subuni...

Environmental Effects on Reactive Oxygen Species Detection—Learning from the Phagosome

Archive ouverte | Nault, Laurent | CCSD

International audience. Abstract Production of reactive oxygen species (ROS) in the phagosome by the NADPH oxidase is critical for mammalian immune defense against microbial infections and phosphoinositides are impo...

ROS production in phagocytes: why, when, and where?

Archive ouverte | Dupré-Crochet, Sophie | CCSD

International audience. ABSTRACT In the phagocytosis field, ROS production by the phagocyte NOX has been associated with pathogen killing for the last 50 years. Since the discovery of nonphagocyte NOX, numerous othe...

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