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Increased Expression of Two Multidrug Transporter-Like Genes Is Associated with Ethidium Bromide and Ciprofloxacin Resistance in Mycoplasma hominis

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Raherison-Semjen, Chantal | Gonzalez, Patrice | Renaudin, H. | Charron, A. | Bébéar, C. | Bébéar, C.M.

Edité par CCSD ; American Society for Microbiology -

International audience. Two genes, md1 and md2 , coding for multidrug resistance ATP-binding cassette transporters were identified in Mycoplasma hominis PG21. Expression of these two genes, quantified by quantitative competitive reverse transcription-PCR, was significantly increased in ethidium bromide-resistant strains of M. hominis compared to that in M. hominis PG21.

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