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CCL17 Production by Dendritic Cells Is Required for NOD1-mediated Exacerbation of Allergic Asthma

Archive ouverte | Ait Yahia, Saliha | CCSD

International audience. Pattern recognition receptors are attractive targets for vaccine adjuvants, and polymorphisms of the innate receptor NOD1 have been associated with allergic asthma.

NOD-like receptors in asthma

Archive ouverte | Alvarez-Simon, Daniel | CCSD

International audience. Asthma is an extremely prevalent chronic inflammatory disease of the airway where innate and adaptive immune systems participate collectively with epithelial and other structural cells to cau...

NOD1 sensing of house dust mite-derived microbiota promotes allergic experimental asthma

Archive ouverte | Ait Yahia, Saliha | CCSD

International audience. BackgroundAsthma severity has been linked to exposure to gram-negative bacteria from the environment that are recognized by NOD1 receptor and are present in house dust mite (HDM) extracts. NO...

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