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p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients.

Archive ouverte | Bourdon, Jean-Christophe | CCSD

International audience. INTRODUCTION: Normal function of the p53 network is lost in most cancers, often through p53 mutation. The clinical impact of p53 mutations in breast cancer remains uncertain, especially where...

Detecting p53 Isoforms at Protein Level

Archive ouverte | Marcel, Virginie | CCSD

International audience

Δ160p53 is a novel N‐terminal p53 isoform encoded by Δ133p53 transcript

Archive ouverte | Marcel, Virginie | CCSD

International audience. p53 gene expresses several protein isoforms modulating p53‐mediated responses through regulation of gene expression. Here, we identify a novel p53 isoform, Δ160p53, lacking the first 159 resi...

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