Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)
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Towns, Clodagh | Richer, Madeleine | Jasaityte, Simona | Stafford, Eleanor, J | Joubert, Julie | Antar, Tarek | Martinez-Carrasco, Alejandro | Makarious, Mary, B | Casey, Bradford | Vitale, Dan | Levine, Kristin | Leonard, Hampton | Pantazis, Caroline, B | Screven, Laurel, A | Hernandez, Dena, G | Wegel, Claire, E | Solle, Justin | Nalls, Mike, A | Blauwendraat, Cornelis | Singleton, Andrew, B | Tan, Manuela, M X | Iwaki, Hirotaka | Morris, Huw, R | Gatto, Emilia, M | Kauffman, Marcelo | Khachatryan, Samson | Tavadyan, Zaruhi | Shepherd, Claire, E | Hunter, Julie | Kumar, Kishore | Ellis, Melina | Rentería, Miguel, E | Koks, Sulev | Zimprich, Alexander | Schumacher-Schuh, Artur, F | Rieder, Carlos | Awad, Paula Saffie | Tumas, Vitor | Camargos, Sarah | Fon, Edward, A | Monchi, Oury | Fon, Ted | Galleguillos, Benjamin Pizarro | Miranda, Marcelo | Bustamante, Maria Leonor | Olguin, Patricio | Chana, Pedro | Tang, Beisha | Shang, Huifang | Guo, Jifeng | Chan, Piu | Luo, Wei | Arboleda, Gonzalo | Orozco, Jorge | del Rio, Marlene Jimenez | Hernandez, Alvaro | Salama, Mohamed | Kamel, Walaa, A | Zewde, Yared, Z | Brice, Alexis | Corvol, Jean-Christophe | Westenberger, Ana | Illarionova, Anastasia | Mollenhauer, Brit | Klein, Christine | Vollstedt, Eva-Juliane | Hopfner, Franziska | Höglinger, Günter | Madoev, Harutyun | Trinh, Joanne | Junker, Johanna | Lohmann, Katja | Lange, Lara, M | Sharma, Manu | Groppa, Sergiu | Gasser, Thomas | Fang, Zih-Hua | Akpalu, Albert | Xiromerisiou, Georgia | Hadjigorgiou, Georgios | Dagklis, Ioannis | Tarnanas, Ioannis | Stefanis, Leonidas | Stamelou, Maria | Dadiotis, Efthymios | Medina, Alex | Chan, Germaine Hiu-Fai | Ip, Nancy | Cheung, Nelson Yuk-Fai | Chan, Phillip | Zhou, Xiaopu | Kishore, Asha | Kp, Divya | Pal, Pramod | Kukkle, Prashanth Lingappa | Rajan, Roopa | Borgohain, Rupam | Salari, Mehri | Quattrone, Andrea | Valente, Enza Maria | Parnetti, Lucilla | Avenali, Micol | Schirinzi, Tommaso | Funayama, Manabu | Hattori, Nobutaka | Shiraishi, Tomotaka | Karimova, Altynay | Kaishibayeva, Gulnaz | Shambetova, Cholpon | Krüger, Rejko | Tan, Ai Huey | Ahmad-Annuar, Azlina | Norlinah, Mohamed Ibrahim | Murad, Nor Azian Abdul | Azmin, Shahrul | Lim, Shen-Yang | Mohamed, Wael | Tay, Yi Wen | Martinez-Ramirez, Daniel | Rodriguez-Violante, Mayela | Reyes-Pérez, Paula | Tserensodnom, Bayasgalan | Ojha, Rajeev | Anderson, Tim, J | Pitcher, Toni, L | Sanyaolu, Arinola | Okubadejo, Njideka | Ojo, Oluwadamilola | Aasly, Jan, O | Pihlstrøm, Lasse | Ur-Rehman, Shoaib | Cornejo-Olivas, Mario | Doquenia, Maria Leila | Rosales, Raymond | Vinuela, Angel | Iakovenko, Elena | Mubarak, Bashayer Al | Umair, Muhammad | Tan, Eng-King | Foo, Jia Nee | Amod, Ferzana | Carr, Jonathan | Bardien, Soraya | Jeon, Beomseok | Kim, Yun Joong | Cubo, Esther | Alvarez, Ignacio | Hoenicka, Janet | Beyer, Katrin | Periñan, Maria Teresa | Pastor, Pau | El-Sadig, Sarah | Zweier, Christiane | Krack, Paul | Lin, Chin-Hsien | Wu, Hsiu-Chuan | Kung, Pin-Jui | Wu, Ruey-Meei | Wu, Yihru | Amouri, Rim | Sassi, Samia Ben | Başak, A. Nazlı | Genc, Gencer | Çakmak, Özgür Öztop | Ertan, Sibel | Noyce, Alastair | Schrag, Anette | Schapira, Anthony | Carroll, Camille | Bale, Claire | Grosset, Donald | Houlden, Henry | Hardy, John | Mok, Kin Ying | Rizig, Mie | Wood, Nicholas | Williams, Nigel | Okunoye, Olaitan | Lewis, Patrick Alfryn | Kaiyrzhanov, Rauan | Weil, Rimona | Love, Seth | Stott, Simon | Jasaitye, Simona | Dey, Sumit | Obese, Vida | Espay, Alberto | O’grady, Alyssa | Sobering, Andrew, K | Siddiqi, Bernadette | Fiske, Brian | Jonas, Cabell | Cruchaga, Carlos | Comart, Charisse | Hall, Deborah | Shiamim, Ejaz | Riley, Ekemini | Faghri, Faraz | Serrano, Geidy, E | Chen, Honglei | Mata, Ignacio, F | Sarmiento, Ignacio Juan Keller | Williamson, Jared | Kim, Jonggeol Jeff | Jankovic, Joseph | Shulman, Joshua | Murphy, Kaileigh | Nuytemans, Karen | Kieburtz, Karl | Markopoulou, Katerina | Marek, Kenneth | Chahine, Lana, M | Ibanez, Laura | Ruffrage, Lauren | Shulman, Lisa | Marsili, Luca | Kuhl, Maggie | Dean, Marissa | Koretsky, Mathew | Puckelwartz, Megan, J | Inca-Martinez, Miguel | Louie, Naomi | Mencacci, Niccolò Emanuele | Albin, Roger | Alcalay, Roy | Walker, Ruth | Bandres-Ciga, Sara | Chowdhury, Sohini | Dumanis, Sonya | Lubbe, Steven | Xie, Tao | Foroud, Tatiana | Beach, Thomas | Sherer, Todd | Song, Yeajin | Nguyen, Duan | Nguyen, Toan | Atadzhanov, Masharip
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CCSD ; Nature -
International audience.
The Global Parkinson’s Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for cohort integration into the complex arm of GP2, and together with our outline of the monogenic hub in a companion paper, provides a generalizable blueprint for establishing large scale collaborative research consortia.
