Cryptococcus neoformans Infections Differ Among Human Immunodeficiency Virus (HIV)–Seropositive and HIV-Seronegative Individuals: Results From a Nationwide Surveillance Program in France
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Paccoud, Olivier | Desnos-Ollivier, Marie | Cassaing, Sophie | Boukris-Sitbon, Karine | Alanio, Alexandre | Bellanger, Anne-Pauline | Bonnal, Christine | Bonhomme, Julie | Botterel, Françoise | Bougnoux, Marie-Elisabeth | Brun, Sophie | Chouaki, Taieb | Cornet, Muriel | Dannaoui, Eric | Demar, Magalie | Desbois-Nogard, Nicole | Durieux, Marie-Fleur | Favennec, Loïc | Fekkar, Arnaud | Gabriel, Frederic | Gangneux, Jean-Pierre | Guitard, Juliette | Hasseine, Lilia | Huguenin, Antoine | Le Gal, Solène | Letscher-Bru, Valérie | Mahinc, Caroline | Morio, Florent | Nicolas, Muriel | Rouges, Célia | Cateau, Estelle | Persat, Florence | Poirier, Philippe | Ranque, Stéphane | Roosen, Gabrielle | Roux, Anne-Laure | Sasso, Milène | Lortholary, Olivier | Lanternier, Fanny | Brieu, N | Durand, C | Bertei, D | Bouchara, J | Pihet, M | Bland, S | Bru, J | Pulik, M | Turdu, F Le | Lefrand, H | Ferrand, M | Larrouy, M | Nevez, G | Quinio, D | Bachelier, M | Coustumier, a Le | Carmagnol, F | Rivière, B | Podac, B | Augereau, O | Emond, J | Bacri, J | Berthelot, G | Dalle, F | Vallee, E | Bizet, J | Noussair, L | Herrmann, J | Brocard, C | Guiffault, P | Layet, A | Morel, A | Penn, P | Gigandon, A | Sendid, B | Cornu, M | Prades, N | Fiacre, T Benoit-Cattin A | Levy, S | Pitsch, A | Kiefer, M | Debourgogne, A | Moquet, O | Colot, J | Courtellemont, L | Poisson, D | Laurens, V | Martres, P | Godineau, N | Picot, S | Chassagne, C | Djibo, N | Devallière, R | Camin-Ravenne, A | Bissuel, F | Janvier, F | Eloy, C | Fur, A | Rezzouk, L | Mazars, E | Eloy, O | Chachaty, E | Mihaila, L | Dellion, S | Patey, O | Thouvenot, A | Limousin, L | Desplaces, N | Raguin, G | Gits-Muselli, M
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CCSD ; Oxford University Press -
International audience.
Among 1107 cryptococcosis cases from the French surveillance network (2005–2020), the proportion of HIV-seronegative individuals has recently surpassed that of HIV-seropositive individuals. We observed marked differences in patient characteristics, disease presentations, cryptococcal antigen results, infecting species, and mortality according to HIV serostatus.
