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Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia

Archive ouverte | Selimoglu-Buet, Dorothée | CCSD

International audience. Key Points An increase in the classical monocyte subset to >94% of total monocytes discriminates CMML from other monocytoses with high specificity. This characteristic increase in classical m...

Disappearance of slan-positive non-classical monocytes for diagnosis of chronic myelomonocytic leukemia with an associated inflammatory state

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CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia

Archive ouverte | Deschamps, Paul | CCSD

International audience. Chronic myelomonocytic leukemia (CMML) is a severe myeloid malignancy with limited therapeutic options. Single-cell analysis of clonal architecture demonstrates early clonal dominance with fe...

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