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WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron

Archive ouverte | Vidal-Petiot, Emmanuelle | CCSD

International audience. Large deletions in the first intron of the With No lysine (K) 1 (WNK1) gene are responsible for Familial Hyperkalemic Hypertension (FHHt), a rare form of human hypertension associated with hy...

Deletion of WNK1 First Intron Results in Misregulation of Both Isoforms in Renal and Extrarenal Tissues

Archive ouverte | Delaloy, Céline | CCSD

International audience. Large deletions in intron 1 of the with-no-lysine kinase type 1 ( WNK1 ) gene cause familial hyperkalemic hypertension. Alternative promoters generate functionally different isoforms: long ub...

Regulation of WNK1 Expression by miR-192 and Aldosterone

Archive ouverte | Elvira-Matelot, Emilie | CCSD

International audience

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