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International audience. The ryanodine receptor (RyR) is the largest known channel, named for specifically binding the alkaloid ryanodine. It is a homotetramer with high conductance for monovalent and divalent cation...

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International audience. Heart Failure (HF) is defined as the inability of the heart to efficiently pump out enough blood to maintain the body's needs, first at exercise and then also at rest. Alterations in Ca 2+ ha...

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