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Altered b lymphocyte homeostasis and functions in systemic sclerosis

Archive ouverte | Forestier, Alexandra | CCSD

International audience. Beyond the production of autoantibodies, B-cells are thought to play a role in systemic sclerosis (SSc) by secreting proinflammatory/profibrotic cytokines. B-cells are a heterogeneous populat...

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Archive ouverte | Sanges, Sébastien | CCSD

International audience. BACKGROUND: There is an ongoing debate regarding the relevance of the 6-minute walking distance (6MWD) in systemic sclerosis (SSc) assessment, widely used as a usual test in these patients as...

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Archive ouverte | Farhat, Méryem-Maud | CCSD

International audience. Systemic lupus erythematosus (SLE) is a chronic autoimmune multi-organ disease with an unpredictable course. SLE causes functional disability, changes in body appearance, and psychological di...

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