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Structural studies of cyclodipeptide synthases with RNA microhelices mimicking their natural tRNA susbtrates

Archive ouverte | Marouf, Zahra | CCSD

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Deciphering the interactions of Cyclodipeptide Synthases with their shortened tRNA substrates by NMR, X-ray crystallography and biophysical approaches

Archive ouverte | Marouf, Zahra | CCSD

National audience. Cyclodipeptide synthases (CDPS) divert aminoacyl-tRNAs to produce cyclodipeptides and complex derivatives, such as diketopiperazines, which constitute a broad class of natural products synthesized...

Molecular bases of the specific recognition of tRNA by cyclodipeptide synthases: Use of RNA microhelices to mimick tRNA acceptor stem

Archive ouverte | Marouf, Zahra | CCSD

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