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A Functional Portrait of Med7 and the Mediator Complex in Candida albicans

Archive ouverte | Tebbji, Faiza | CCSD

International audience. Mediator is a multi-subunit protein complex that regulates gene expression in eukaryotes by integrating physiological and developmental signals and transmitting them to the general RNA polyme...

Three members of the yeast N-BAR proteins family form heterogeneous lattices in vivo and interact differentially with two RabGAP proteins

Archive ouverte | Prigent, Magali | CCSD

International audience. The yeast N-BAR (Bin/Amphiphysin/Rvs167) protein Rvs167 is recruited by the Rab GTPase Activating Proteins (RabGAP) Gyp5 and Gyl1 to the tip of small buds to act in exocytosis. Investigating ...

Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor.

Archive ouverte | Menant, Alexandra | CCSD

In yeast, the Met4 transcription factor and its cofactors Cbf1, Met28, Met31, and Met32 control the expression of sulfur metabolism and oxidative stress response genes. Met4 activity is tuned to nutrient and oxidative stress condi...

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