Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes

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Zubiaga, Lorea | Briand, Olivier | Auger, Florent | Touche, Veronique | Hubert, Thomas | Thevenet, Julien | Marciniak, Camille | Quenon, Audrey | Bonner, Caroline | Peschard, Simon | Raverdy, Violeta | Daoudi, Mehdi | Kerr-Conte, Julie | Pasquetti, Gianni | Koepsell, Hermann | Zdzieblo, Daniela | Mühlemann, Markus | Thorens, Bernard | Delzenne, Nathalie, D | Bindels, Laure, B | Deprez, Benoit | Vantyghem, Marie, C | Laferrère, Blandine | Staels, Bart | Huglo, Damien | Lestavel, Sophie | Pattou, François

Edité par CCSD ; Elsevier -

International audience. Highlights Metformin transiently reduces SGLT1 apical expression in enterocytes Metformin acutely reduces SGLT1-mediated enterocyte glucose uptake Oral metformin acutely reduces SGLT1-mediated post-prandial glucose response

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