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MicroScope: an integrated platform for the annotation and exploration of microbial gene functions through genomic and metabolic comparative analysis
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International audience. Large-scale genome sequencing and the increasingly massive use of high-throughput approaches produce a vast amount of new information that completely transforms our understanding of thousands of microbial species. However, despite the development of powerful bioinformatics approaches, full interpretation of the content of these genomes remains a difficult task. To address this challenge, we have developed the MicroScope platform [1,2], which is a software environment for management, annotation, comparative analysis and visualization of microbial genomes (https://www.genoscope.cns.fr/agc/microscope). Published for the first time in 2006 [3], the platform has been under continuous development within the LABGeM group at Genoscope and provides analysis for complete and ongoing genome projects together with post-genomic experiments allowing users to improve the understanding of gene functions. 1. Vallenet D, et al. MicroScope in 2017: an expanding and evolving integrated resource for community expertise of microbial genomes. Nucleic Acids Res. Oxford University Press; 2016;45: D517–D528.2. Médigue C, et al. MicroScope—an integrated resource for community expertise of gene functions and comparative analysis of microbial genomic and metabolic data. Brief Bioinform. 2017;3. Vallenet D, et al. MaGe: a microbial genome annotation system supported by synteny results. Nucleic Acids Res. Oxford University Press; 2006;34: 53–65.
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